Quality improvement effort cuts blood clots in brain injury patients

(HealthDay)—Implementation of an anticoagulation protocol reduces blood clots in patients with traumatic brain injury (TBI), according to a study published in the April 1 issue of The Joint Commission Journal on Quality and Patient Safety.

Christopher J. Tignanelli, M.D., from the University of Minnesota Medical School in Minneapolis, and colleagues evaluated the institutional implementation of a prophylactic anticoagulation protocol in patients with TBI. The analysis included 681 patients with TBI (368 preimplementation and 313 postimplementation).

The researchers found that after implementation of the venous thromboembolism (VTE) protocol, more patients received anticoagulation (preprotocol: 39.4 percent; postprotocol: 80.5 percent), time to initiation was shorter (preprotocol: 140 hours; postprotocol: 59 hours), and there were fewer VTE events (preprotocol: 5.2 percent; postprotocol: 2.2 percent). Postprotocol patients were significantly more likely to receive anticoagulation (odds ratio, 10.8; 95 percent confidence interval, 6.9 to 16.7; P < 0.001) and less likely to develop VTE (odds ratio, 0.33; 95 percent confidence interval, 0.1 to 1.0; P = 0.05).

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