New insights into eye damage in Alzheimer’s disease patients

New insights: Eye damage in Alzheimer's disease patients

  • An overabundance of a protein called amyloid beta 42, which in the brains of Alzheimer’s disease patients clumps together to form plaques that disrupt brain function
  • Accumulation of amyloid beta protein in ganglion cells, the cells that bridge visual input from the retina to the optic nerve
  • Higher numbers of astrocytes and immune cells, called microglia, tightly surrounding amyloid beta plaques
  • As many as 80% fewer microglial cells clearing amyloid beta proteins from the retina and brain
  • Specific molecules and biological pathways responsible for inflammation, and cell and tissue death

Source: Read Full Article