There aren’t enough ventilators in the United States to keep alive the hundreds of thousands of people who will need them during the COVID-19 pandemic. There may be a stopgap, however.
Doctors can reconfigure existing ventilators so that these lifesaving devices serve either two or four patients simultaneously, rather than just one at a time, according to a 2006 feasibility study in the journal Academic Emergency Medicine.
The study was written in the aftermath of 9/11 and Hurricane Katrina, but in light of the new coronavirus outbreak, one of the study’s authors published a YouTube tutorial to show how this idea could work for patients whose breathing is impaired by the new coronavirus.
“In that study, we just looked at simple equipment available in the emergency department and a way to modify the ventilator to ventilate four patients,” study co-author Dr. Charlene Irvin Babcock, an emergency medicine physician at St. John Hospital and Medical Center in Detroit, said in the video.
A ventilator is a machine that can help a person breathe by delivering oxygen through a tube placed in the mouth or nose, or through a hole in the front of the neck, according to the Centers for Disease Control and Prevention.
In essence, the study shows that a ventilator can be modified with adapters and T-shaped tubes so that it has four ports for four patients, said Babcock, who co-wrote the study with Dr. Greg Neyman. At the time, Neyman was a resident in emergency medicine at St. John Hospital and Medical Center, and now works as an emergency physician at several hospitals in Hamilton, New Jersey.
Their experiment simulated four adults weighing 154 lbs. (70 kilograms) getting ventilation for 12 hours. However, Babcock cautioned that transforming a ventilator this way is “off label,” meaning that it’s not approved by the Food and Drug Administration. Moreover, it was never studied in people; the 2006 study merely used lung simulators, rather than human subjects.
But this idea was put to use by Dr. Kevin Menes, an emergency room physician who treated mass shooting victims at the 2017 Las Vegas country music concert. Menes had been a resident with Neyman, so he was aware of the ventilator study. (You can read about Menes’ harrowing night at Sunrise Hospital in Las Vegas here.)
“You can imagine that with a lot of penetrating torso and CNS [central nervous system] injuries, [Menes] intubated a lot of patients,” Babcock said. “They received a large volume of patients very quickly and they ran out of ventilators.”
So, Menses directed that each ventilator get reconfigured with one T-tube so it could serve two patients. “It was very successful,” Babcock said. “He was able to keep them alive for hours as they waited for outside ventilator supports to come in and help them supply the patient need.”
Using a ventilator for multiple people isn’t easy. Doctors would have to pair together patients with similar lung sizes. “You wouldn’t want to put a pediatric patient with an adult patient, because that wouldn’t make sense,” Irwin said. “It wouldn’t be able to ensure that the same volume [of oxygen] is delivered everywhere appropriately.”
Furthermore, patients need to be breathing with the same resistance to the ventilator’s oxygen flow. “You wouldn’t want to put a patient with severe bronchospasm with a patient who did not have bronchospasm,” a condition in which the muscles tighten in the lungs, which can make breathing difficult, Irwin said. That’s because people breathing with different resistances “might change the amount of volumes, and it wouldn’t make sure that there were equal volumes delivered to everybody,” she said.
Using the same ventilator for multiple people could spread germs, but in this case, these patients would have COVID-19 already anyway, Babcock noted. In addition, the patients would need to be sedated for this to work, Babcock added in the YouTube comments.
But this setup is designed to be a temporary one, used only when there is a “disaster surge involving multiple casualties with respiratory failure,” the researchers wrote in the study. COVID-19 patients typically need artificial ventilation for longer than 12 hours, the amount of time analyzed in the study. And if one patient improves and needs less oxygen, while another worsens and needs more, a ventilator hooked up to two people could not adjust to both of them, as ProPublica reported. Getting too little or too much oxygen can damage the lungs.
“I have never heard of ventilators being shared between multiple patients as the process of ventilation is very personal — the controls and sensors are set to satisfy an individual patient[‘s] needs and wellbeing,” Mark Tooley, a fellow at the Royal Academy of Engineering in the United Kingdom, told MailOnline in response to the video and study. “‘The risk of infection would also be high if used for seriously ill patients. In theory it could be possible, but it would be a very complex procedure, fraught with issues.”
In the meantime, states are frantically trying to acquire ventilators. For instance, Democratic Gov. Andrew Cuomo announced that New York has procured about 7,000 ventilators, but needs at least 30,000 more, according to ABC News. Some companies are also switching gears to make them, including SpaceX and Tesla, run by Elon Musk, Live Science previously reported.
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Originally published on Live Science.
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