Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Nov. 16 to 20, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
FDA Issues EUA to Baricitinib Plus Remdesivir for COVID-19
FRIDAY, Nov. 20, 2020 — Emergency use authorization was issued for baricitinib in combination with remdesivir for hospitalized patients with COVID-19, the U.S. Food and Drug Administration announced Thursday.
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High-Dose Anticoagulation May Not Aid COVID-19 Patients
FRIDAY, Nov. 20, 2020 — Higher doses of blood thinners are potentially harmful and have no clear benefits for hospitalized COVID-19 patients, according to a study published online Nov. 5 in Thrombosis Research.
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Behavioral, Psych Condition Care Shifted to Telemedicine During COVID-19
FRIDAY, Nov. 20, 2020 — Office-based visits for behavioral and psychiatric conditions decreased in association with the COVID-19 pandemic, although increases in telemedicine visits offset these decreases, according to a research letter published online Nov. 17 in the Annals of Internal Medicine.
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Predictors of Severe Disease ID’d in Children With SARS-CoV-2
THURSDAY, Nov. 19, 2020 — Predictors of severe disease have been identified for children with severe acute respiratory syndrome coronavirus 2, according to a study published online Nov. 13 in The Journal of Pediatrics.
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COVID-19-Related Job Insecurity Tied to Anxiety, Depression
THURSDAY, Nov. 19, 2020 — Job insecurity as a result of the COVID-19 pandemic is associated with self-reported anxiety and depression among U.S. young adults, according to a study published online Nov. 9 in the Journal of Adolescent Health.
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U.S. COVID-19 Deaths Top a Quarter Million
THURSDAY, Nov. 19, 2020 — The United States crossed a grim threshold on Wednesday: More than 250,000 Americans have now died from COVID-19.
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Pandemic Affecting Young People’s Mental Health
WEDNESDAY, Nov. 18, 2020 — Nearly half of U.S. young adults report symptoms of depression, with more than one-third reporting thoughts of death or suicide, according to the results of a survey released by the COVID-19 Consortium for Understanding the Public’s Policy Preferences Across States.
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Fluvoxamine Linked to Reduction in Clinical Deterioration in COVID-19
WEDNESDAY, Nov. 18, 2020 — For adult outpatients with COVID-19, fluvoxamine is associated with a reduction in clinical deterioration, according to a study published online Nov. 12 in the Journal of the American Medical Association.
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AAP Urges Inclusion of Children in SARS-CoV-2 Vaccine Trials
WEDNESDAY, Nov. 18, 2020 — Children should be included in clinical trials for a severe acute respiratory syndrome coronavirus 2 vaccine at the earliest stages, according to a letter from the president of the American Academy of Pediatrics, on behalf of more than 67,000 pediatricians and pediatric medical and surgical subspecialists.
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FDA Approves First Rapid COVID-19 Test for Home Use
WEDNESDAY, Nov. 18, 2020 — The first rapid COVID-19 test that can be taken at home with results delivered in 30 minutes was cleared for emergency use by the U.S. Food and Drug Administration on Tuesday.
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Sixty-Day Outcomes Examined for Hospitalized COVID-19 Patients
TUESDAY, Nov. 17, 2020 — Almost 30 percent of patients hospitalized with COVID-19 died during hospitalization or within 60 days after discharge, according to a research letter published online Nov. 11 in the Annals of Internal Medicine.
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Routine COVID-19 Testing Improves Safety of Elective Surgery
TUESDAY, Nov. 17, 2020 — Preoperative nasopharyngeal swab testing is beneficial before major surgery and in high severe acute respiratory syndrome coronavirus 2-risk areas, according to a study published in the British Journal of Surgery.
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Major U.S. Medical Groups Urge Trump to Work With Biden on Fighting COVID-19
TUESDAY, Nov. 17, 2020 — U.S. President Donald Trump needs to work with President-Elect Joe Biden to fight the COVID-19 pandemic as the country grapples with record-breaking numbers of new cases, the American Medical Association, American Nurses Association, and American Hospital Association say in a letter to Trump.
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Nebulized Interferon Beta-1a Promising for COVID-19
TUESDAY, Nov. 17, 2020 — Patients hospitalized with COVID-19 who receive inhaled nebulized interferon beta-1a have greater odds of improvement than those receiving placebo, according to a study published online Nov. 12 in The Lancet Respiratory Medicine.
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Persistent Fatigue Prevalent After COVID-19 Infection
TUESDAY, Nov. 17, 2020 — For individuals who have recovered from the acute phase of COVID-19, postviral fatigue is prevalent and is not associated with COVID-19 severity, according to a study published online Nov. 9 in PLOS ONE.
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Hospital Mortality Higher for Critically Ill With COVID-19 Versus Flu
TUESDAY, Nov. 17, 2020 — The risk for hospital mortality is higher for critically ill patients with COVID-19 infection compared with influenza, according to a study published online Nov. 13 in the Annals of the American Thoracic Society.
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AKI Common in U.S. Veterans Hospitalized With COVID-19
MONDAY, Nov. 16, 2020 — Acute kidney injury is common among U.S. veterans hospitalized with COVID-19 and is associated with an increased risk for health care resource utilization and death, according to a study published online Nov. 16 in the Clinical Journal of the American Society of Nephrology.
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OCD Symptoms Worsening Among Children During COVID-19
MONDAY, Nov. 16, 2020 — Many children and adolescents with obsessive-compulsive disorder have experienced a worsening of their symptoms during the COVID-19 crisis, according to a study published online Oct. 20 in BMC Psychiatry.
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Pfizer COVID-19 Vaccine Could Cut Transmission by Half: Company Executive
MONDAY, Nov. 16, 2020 — The BioNTech and Pfizer experimental COVID-19 vaccine could cut transmission of the virus in half, leading to a “dramatic” curb of its spread, according to a company executive.
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SARS-CoV-2 Transmitted Despite Quarantine Conditions
MONDAY, Nov. 16, 2020 — Transmission of severe acute respiratory syndrome coronavirus 2 can occur even under supervised quarantine conditions, according to a study published online Nov. 11 in the New England Journal of Medicine.
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Moderna Vaccine Shows 94.5 Percent Effectiveness Against COVID-19
MONDAY, Nov. 16, 2020 — Moderna Inc. announced on Monday that early results show its COVID-19 vaccine is 94.5 percent effective.
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